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Systematic review and evidence-based clinical recommendations for dosing of pediatric supported standing programs

date: 2013 Fall;25(3):232-47
author: Paleg GS, Smith BA, Glickman LB.
publication: Pediatr Phys Ther.
PubMed ID: 23797394

Abstract

PURPOSE:
There is a lack of evidence-based recommendations for effective dosing of pediatric supported standing programs, despite widespread clinical use.
METHODS:
Using the International Classification of Functioning, Disability, and Health (Child and Youth Version) framework, we searched 7 databases, using specific search terms.
RESULTS:
Thirty of 687 studies located met our inclusion criteria. Strength of the evidence was evaluated by well-known tools, and to assist with clinical decision-making, clinical recommendations based on the existing evidence and the authors’ opinions were provided.
CONCLUSIONS AND RECOMMENDATIONS FOR CLINICAL PRACTICE:
Standing programs 5 days per week positively affect bone mineral density (60 to 90 min/d); hip stability (60 min/d in 30° to 60° of total bilateral hip abduction); range of motion of hip, knee, and ankle (45 to 60 min/d); and spasticity (30 to 45 min/d).

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Systematic review and clinical recommendations for dosage of supported home-based standing programs for adults with stroke, spinal cord injury and other neurological conditions

date: 17 November 2015.
author: Paleg G., Livingstone R.
publication: BMC Musculoskeletal Disorders
PubMed ID: 26576548

Abstract

Background
Sitting for more than 8 h a day has been shown to negatively impact health and mortality while standing is the recommended healthier alternative. Home-based standing programs are commonly recommended for adults who cannot stand and/or walk independently. The aim of this systematic review is to review effectiveness of home-based standing programs for adults with neurological conditions including stroke and spinal cord injury; and to provide dosage guidelines to address body structure and function, activity and participation outcomes.
Methods
Eight electronic databases were searched, including Cochrane Library databases, MEDLINE, CINAHL and EMBASE. From 376 articles, 36 studies addressing impact of a standing intervention on adults with sub-acute or chronic neurological conditions and published between 1980 and September 2015 were included. Two reviewers independently screened titles, reviewed abstracts, evaluated full-text articles and rated quality and strength of evidence. Evidence level was rated using Oxford Centre for Evidence Based Medicine Levels and quality evaluated using a domain-based risk-of-bias rating. Outcomes were divided according to ICF components, diagnoses and dosage amounts from individual studies. GRADE and the Evidence-Alert Traffic-Lighting system were used to determine strength of recommendation and adjusted in accordance with risk-of-bias rating.
Results
Stronger evidence supports the impact of home-based supported standing programs on range of motion and activity, primarily for individuals with stroke or spinal cord injury while mixed evidence supports impact on bone mineral density. Evidence for other outcomes and populations is weak or very weak.
Conclusions
Standing should occur 30 min 5 times a week for a positive impact on most outcomes while 60 min daily is suggested for mental function and bone mineral density.

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Greta – Cerebral Palsy – spastic, quadriplegic

Brief description of environment of facility/school

Greta is served through  Early Intervention with a trans-disciplinary, family routines-based model and Physical Therapist as primary service provider.

Basic Info about client

  • Greta
  • Age: 30 months
  • Diagnosis: Cerebral Palsy – spastic, quadriplegic
  • Brief history:
    • born after an uncomplicated pregnancy at 39 3/7 weeks
    • at birth, she had a heart rate of 92 but no spontaneous respirations
    • Apgars were 3 at birth; 4 at one minute; and 4 at ten minutes
    • shortly after birth, Greta had Sarnat stage III encephalopathy and on admission to Newborn Intensive Care Unit at 2 ½ hours of age, she had stage II encephalopathy
    • initial EEG showed occasional electrographic seizures. She was cooled for 72 hours and her EEG showed improvement
    • receives regularly scheduled botulinum toxin injections to most affected areas (usually upper extremity)
    • had trial of Sinemet for motor function, but drug was discontinued due to gastrointestinal side effects (vomiting)

Continue reading Greta – Cerebral Palsy – spastic, quadriplegic

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Eli – Cerebral Palsy

Basic Info about client

Client’s Name: Eli
Age: 2 (will be 3 on 4/2/15)
Diagnosis: Cerebral Palsy
Brief history:
Premature birth – 35 weeks gestation
Sustained intrauterine ischemic event with damage to left parietal lobe, right occipital lobe, Macrodactyly left foot
Current Situation: Eli’s primary means of independent mobility is crawling with a non-reciprocating “bunny hop” pattern. He crawls up and down stairs and pulls to standing independently. He has decreased function of his right upper extremity, but consistently uses his right “helper hand”. Spasticity is present through both legs and right arm. Eli demonstrates typical crouch gait alignment in standing, tending toward bilateral ankle plantarflexion, and flexion at both knees and hips. He propels a gait trainer with minimal assist with forearm prompts and does best with ankle prompts to minimize scissoring and anterior rotation of the left side of the body. He requires verbal prompting to step to or step through with his right foot. Eli has bilateral Ankle Foot Orthotics (AFOs) to assist with alignment of his feet and lower legs. Continue reading Eli – Cerebral Palsy

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Dempsey – Achondroplasia, Cerebral Palsy

Brief description of environment of facility/school

Dempsey is seen by his school district’s Early Intervention team, with visits from the Physical Therapist twice per month as primary service provider with consultation from Early Childhood Special Education teacher and Service Coordinator.

Basic Info about client

Clients Name – Dempsey
Age – 10 months
Diagnosis – achondroplasia, cerebral palsy
Brief history – Dempsey’s mother experienced premature preterm rupture of membranes (PPROM) at 31 weeks, 3 days gestation and was hospitalized. Dempsey was delivered at 34 weeks, 1 day gestation with birth weight of 2400 grams. His Apgar scores were 3 at 1 minute and 8 at 5 minutes. He required positive pressure ventilation with oxygen and had ongoing care in the NICU for respiratory distress syndrome. MRI indicated severe hypoxic ischemic injury, multifocal cerebral, cerebellar, and intraventricular areas of microhemorrhage. Continue reading Dempsey – Achondroplasia, Cerebral Palsy

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Cardiovascular response of individuals with spinal cord injury to dynamic functional electrical stimulation under orthostatic stress

date: 2013 Jan;21(1):37-46.
author: Yoshida T.
publication: IEEE Trans Neural Syst Rehabil Eng.
PubMed ID: 22899587

Abstract

In this pilot study, we examined how effectively functional electrical stimulation (FES) and passive stepping mitigated orthostatic hypotension in participants with chronic spinal cord injury (SCI). While being tilted head-up to 70 (°) from the supine position, the participants underwent four 10-min conditions in a random sequence: 1) no intervention, 2) passive stepping, 3) isometric FES of leg muscles, and 4) FES of leg muscles combined with passive stepping. We found that FES and passive stepping independently mitigated a decrease in stroke volume and helped to maintain the mean blood pressure. The effects of FES on stroke volume and mean blood pressure were greater than those of passive stepping. When combined, FES and passive stepping did not interfere with each other, but they also did not synergistically increase stroke volume or mean blood pressure. Thus, the present study suggests that FES delivered to lower limbs can be used in individuals with SCI to help them withstand orthostatic stress. Additional studies are needed to confirm whether this use of FES is applicable to a larger population of individuals with SCI.

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Comparison of orthostatic reactions of patients still unconscious within the first three months of brain injury on a tilt table with and without integrated stepping. A prospective, randomized crossover pilot trial.

date: 2008 Dec;22(12):1034-41
author: Luther MS
publication: Clin Rehabil
PubMed ID: 19052242

Abstract

OBJECTIVE:

To determine whether passive leg movement during tilt table mobilization reduces the incidence of orthostatic dysfunction in mobilization of patients being comatose or semi-comatose early after brain injury.

DESIGN:

Randomized crossover pilot trial using sequential testing.

SETTING:

Neurorehabilitation hospital.

SUBJECTS:

Nine patients still unconscious within the first three months of brain injury (5 men, 4 women; age 51 +/- 20 years).

INTERVENTION:

Patients were subjected once to a conventional tilt table and once to a tilt table with an integrated stepping device.

MAIN OUTCOME MEASURE:

The number of syncopes/presyncopes (orthostatic hypotension, tachypnoea, increased sweating) during interventions.

RESULTS:

One patient had presyncopes on both devices, six patients had presyncopes on the conventional tilt table but not on the tilt table with integrated stepping, and two patients did not exhibit presyncopal symptoms on either device. There were significantly more incidents on the tilt table without than on the one with an integrated stepping device (P < 0.05) at tilts of 50 or 70 degrees respectively.

CONCLUSION:

Patients tolerate greater degrees of head-up tilt better with simultaneous leg movement.

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Investigation of robotic-assisted tilt-table therapy for early-stage spinal cord injury rehabilitation.

date: 2013;50(3):367-78.
author: Craven CTD.
publication: J Rehabil Res Dev
PubMed ID: 23881763

Abstract

Damage to the spinal cord compromises motor function and sensation below the level of injury, resulting in paralysis and progressive secondary health complications. Inactivity and reduced energy requirements result in reduced cardiopulmonary fitness and an increased risk of coronary heart disease and cardiovascular complications. These risks may be minimized through regular physical activity. It is proposed that such activity should begin at the earliest possible time point after injury, before extensive neuromuscular degeneration has occurred. Robotic-assisted tilt-table therapy may be used during early-stage spinal cord injury (SCI) to facilitate stepping training, before orthostatic stability has been achieved. This study investigates whether such a stimulus may be used to maintain pulmonary and coronary health by describing the acute responses of patients with early-stage (<1 yr) motor-complete SCI (cSCI) and motor-incomplete SCI (iSCI) to passive, active, and electrically stimulated robotic-assisted stepping. Active participation was found to elicit an increased response from iSCI patients. The addition of electrical stimulation did not consistently elicit further increases. Extensive muscle atrophy was found to have occurred in those patients with cSCI, thereby limiting the potential effectiveness of electrical stimulation. Active participation in robotic-assisted tilt-table therapy may be used to improve cardiopulmonary fitness in iSCI patients if implemented as part of a regular training program.

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Electrically induced and voluntary activation of physiologic muscle pump: a comparison between spinal cord-injured and able-bodied individuals.

date: 2002 Dec;16(8):878-85.
author: Faghri PD.
publication: Clin Rehabil
PubMed ID:12501950

Abstract

OBJECTIVE:

To evaluate the central haemodynamic responses during position changes from supine to sitting and during 30 min of standing between able-bodied and spinal cord-injured subjects. Also to assess the effects of the physiologic muscle pump in both groups during 30 min of standing.

DESIGN:

A repeated measure design. Both groups were tested on two different days under two conditions of 30 min of stationary standing and 30 min of dynamic standing (voluntary activation of the lower leg muscles in able-bodied and FES-induced activation of these muscles in spinal cord injured). The order of testing was random.

SETTING:

Rehabilitation hospital.

SUBJECTS:

Fifteen healthy able-bodied and 14 healthy spinal cord-injured subjects.

MAIN OUTCOME MEASURED:

Stroke volume, cardiac output, heart rate, systolic blood pressure, diastolic blood pressure, mean arterial pressure and total peripheral resistance during supine-pre sitting, sitting-pre standing and during 30 min of standing.

RESULTS:

Significant reductions (p < 0.05) in systolic blood pressure, diastolic blood pressure and mean arterial pressure were found when spinal cord-injured subjects moved from sitting to standing during stationary standing; these values were maintained during dynamic standing. These values were maintained during both standing sessions in able-bodied subjects. During 30 min of stationary standing, there were significant reductions in stroke volume, cardiac output in both able-bodied and spinal cord-injured while their total peripheral resistance increased (p < 0.05). During 30 min of dynamic standing, both groups maintained their haemodynamics at pre-standing values with the exception of significant reduction in stroke volume at 30 min of standing.

CONCLUSION:

FES-induced activation of the physiologic muscle pump during change in position from sitting to standing prevented orthostatic hypotension in spinal cord-injured subjects. During standing it had equal or even greater effect on improving blood circulation when compared with voluntary activation in able-bodied subjects. The use of FES during standing and tilting in spinal cord-injured individuals may prevent orthostatic hypotension and circulatory hypokinesis and improve tolerance to tilting and standing.